Combined epidural and general anaesthesia versus general anaesthesia for abdominal aortic surgery : a prospective randomised trial

Fifty patients undergoing elective abdominal aortic surgery were randomised to receive either combined epidural and general anaesthesia and postoperative epidural analgesia (CEGA) or general anaesthesia and postoperative intravenous morphine infusion (GA). Prospective data was collected in order to...

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Bibliographic Details
Published in:Anaesthesia and intensive care 1993-12, Vol.21 (6), p.790-794
Main Authors: DAVIES, M. J, SILBERT, B. S, MOONEY, P. J, DYSART, R. H, MEADS, A. C
Format: Article
Language:English
Subjects:
Aged
Analgesia - methods
Analgesia, Epidural
Anesthesia
Anesthesia depending on type of surgery
Anesthesia, Epidural
Anesthesia, General
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Aorta, Abdominal - surgery
Aortic Diseases - surgery
Biological and medical sciences
Bupivacaine - administration & dosage
Ephedrine - therapeutic use
Female
Follow-Up Studies
Humans
Infusions, Intravenous
Intraoperative Care
Male
Medical sciences
Metaraminol - therapeutic use
Morphine - administration & dosage
Nitroglycerin - therapeutic use
Pain, Postoperative - prevention & control
Postoperative Complications
Prospective Studies
Thoracic and cardiovascular surgery. Cardiopulmonary bypass
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Summary:Fifty patients undergoing elective abdominal aortic surgery were randomised to receive either combined epidural and general anaesthesia and postoperative epidural analgesia (CEGA) or general anaesthesia and postoperative intravenous morphine infusion (GA). Prospective data was collected in order to compare the two groups. This included intraoperative cardiovascular changes and postoperative complications. The use of intraoperative vasopressors was significantly higher in the CEGA group (P < 0.01) but the use of intravenous glyceryl trinitrate was significantly lower (P < 0.01). There was no significant difference between groups in regard to blood loss, volume replacement or in the number of patients requiring postoperative ventilation. Two patients in the CEGA group died postoperatively compared to one in the GA group (not significant). There was no significant difference between groups in the total number or type of postoperative complications. Combining epidural anaesthesia with general anaesthesia altered intraoperative cardiovascular management but did not affect postoperative outcome.
ISSN:0310-057X
1448-0271
DOI:10.1177/0310057x9302100607