Filtration of shed mediastinal blood

Re-infusion of shed blood carries the risk of re-infusing cellular debris. All re-infusion devices have some sort of integral filtration which is variably supple mented with a second intravenous filter. Using electron microscopy we have observed what debris is collected by secondary filtration. In 1...

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Bibliographic Details
Published in:Perfusion 1993, Vol.8 (4), p.331-336
Main Authors: Fox, Mark A, Kent, Andrew P, Fraser, Scott R, Wilkins, Karen M, Kendall, Karen N
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Cells - pathology
Blood Loss, Surgical
Blood Transfusion, Autologous - adverse effects
Blood Transfusion, Autologous - instrumentation
Blood Transfusion, Autologous - methods
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
Equipment Safety
Evaluation Studies as Topic
Health technology assessment
Hemofiltration - instrumentation
Hemofiltration - methods
Humans
Medical sciences
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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Summary:Re-infusion of shed blood carries the risk of re-infusing cellular debris. All re-infusion devices have some sort of integral filtration which is variably supple mented with a second intravenous filter. Using electron microscopy we have observed what debris is collected by secondary filtration. In 12 patients studied, nine out of 12 filters had significant amounts of cellular debris present, but not clearly related to increased rates of postoperative bleeding. Noncellular debris, silicon and strands of cellulose were also observed. Although we have not detected any clinically significant embolic phenomena from re-infusion of shed mediastinal blood, it seems prudent to include a second filter prior to re-infusion.
ISSN:0267-6591
1477-111X
DOI:10.1177/026765919300800408