Controlled-release oxycodone for the management of pediatric postoperative pain

Studies addressing pain management after pediatric spinal fusion surgery have focused on the use of patient-controlled or epidural analgesia during the immediate postoperative period. Controlled-release (CR) analgesics have been found to be safe and effective in adults. The purpose of this study was...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pain and symptom management 2004-04, Vol.27 (4), p.379-386
Main Authors: Czarnecki, Michelle L., Jandrisevits, Matthew D., Theiler, Sarah C., Huth, Myra Martz, Weisman, Steven J.
Format: Article
Language:English
Subjects:
Adolescent
Analgesics, Opioid - administration & dosage
Analgesics, Opioid - adverse effects
Biological and medical sciences
Child
controlled-release analgesics
Delayed-Action Preparations
Female
Humans
Male
Medical sciences
oxycodone
Oxycodone - administration & dosage
Oxycodone - adverse effects
oxycodone-CR
pain management
Pain, Postoperative - drug therapy
Pediatric
Pharmacology. Drug treatments
postoperative pain
Retrospective Studies
spine fusion
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Studies addressing pain management after pediatric spinal fusion surgery have focused on the use of patient-controlled or epidural analgesia during the immediate postoperative period. Controlled-release (CR) analgesics have been found to be safe and effective in adults. The purpose of this study was to describe the use of oxycodone-CR in pediatric patients after the immediate postoperative period. A retrospective chart review of 62 postoperative spinal fusion patients (10-19 years) was conducted. The mean initial oxycodone-CR dose was 1.24 mg/kg/day. The mean ratio of conversion from parenteral morphine equivalents to oxycodone-CR was 1:1. Mean pain scores decreased from 4.2/10 to 3.7/10 with the transition to oxycodone-CR. Common side effects included dizziness, constipation, and nausea. Oxycodone-CR was used for an average of 13.3 days, which included an average wean time of 6 days. Results of this study demonstrate safe and effective use of oxycodone-CR in the pediatric spinal fusion population.
ISSN:0885-3924
1873-6513
DOI:10.1016/j.jpainsymman.2003.08.007