The effect of internal fixation on the healing of large allografts

One hundred and twenty patients had an allograft reconstruction of the femur, tibia, or humerus. Of a total of 183 allograft-host junctions, eight-three were fixed with a plate; ninety-eight, with an intramedullary rod; and two, with screws alone. There was no significant difference between the rate...

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Bibliographic Details
Published in:Journal of bone and joint surgery. American volume 1994-05, Vol.76 (5), p.657-663
Main Author: Vander Griend, R A
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Ankle Joint - surgery
Arthroplasty
Biological and medical sciences
Bone Nails
Bone Neoplasms - surgery
Bone Plates
Bone Regeneration
Bone Screws
Bone Transplantation - adverse effects
Bone Transplantation - methods
Chi-Square Distribution
Child
Female
Femur - surgery
Fracture Healing - physiology
Fractures, Spontaneous - etiology
Humans
Humerus - surgery
Internal Fixators - adverse effects
Knee Joint - surgery
Logistic Models
Male
Medical sciences
Middle Aged
Orthopedic surgery
Shoulder Joint - surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tibia - surgery
Transplantation, Homologous - methods
Treatment Failure
Weight-Bearing
Wound Healing
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Description
Summary:One hundred and twenty patients had an allograft reconstruction of the femur, tibia, or humerus. Of a total of 183 allograft-host junctions, eight-three were fixed with a plate; ninety-eight, with an intramedullary rod; and two, with screws alone. There was no significant difference between the rate of union after fixation with a plate and that after intramedullary fixation (p = 1.00). However, fixation with a plate was associated with a higher rate of fracture of the allograft (p < 0.0001). Some problem related to the internal fixation of the allograft was identified at eighteen of the twenty junctions that did not heal. There was a significant association (p < 0.001) between a problem in the achievement of stable fixation and the development of a non-union at the allograft-host junction.
ISSN:0021-9355
1535-1386
DOI:10.2106/00004623-199405000-00005