Adverse Impact of Hypertension on Diabetic Recipients of Transplanted Kidneys

The effect of hypertension on patient and allograft survival in 60 diabetic recipients of transplanted kidneys was assessed by retrospective chart analysis. Hypertension was present in 81 % of recipients. Of eight of these patients who became normotensive after transplantation, all had functioning a...

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Bibliographic Details
Published in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 1985-11, Vol.7 (6 Suppl II), p.II-131-II-134
Main Authors: FRIEDMAN, ELI A, CHOU, LUCIA M, BEYER, MONICA M, BUTT, KHALID M.H, MANIS, THOMAS
Format: Article
Language:English
Subjects:
Aged
Blood Pressure
Diabetes Complications
Diabetic Nephropathies - mortality
Diabetic Nephropathies - surgery
Humans
Hypertension - complications
Hypertension - physiopathology
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - surgery
Kidney Transplantation
Middle Aged
Retrospective Studies
Time Factors
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Summary:The effect of hypertension on patient and allograft survival in 60 diabetic recipients of transplanted kidneys was assessed by retrospective chart analysis. Hypertension was present in 81 % of recipients. Of eight of these patients who became normotensive after transplantation, all had functioning allografts and one died. By contrast, persistent hypertension after transplantation was associated with a higher mortality rate (25 of 54, 48%) and loss of kidney graft function (19 of 54, 35%). At a mean of 21 months after transplantation, living hypertensive diabetic recipients had worse renal function (mean serum creatinine of 3.1 mg/dl) than did nonhypertensive recipients (mean serum creatinine of 1.6 mg/dl). It is concluded that hypertension is a significant risk factor for diabetic patients and kidneys after transplantation.
ISSN:0194-911X
1524-4563
DOI:10.1161/01.hyp.7.6_pt_2.ii131