In vivo measurement of myocardial mass using nuclear magnetic resonance imaging

To examine the accuracy of nuclear magnetic resonance imaging in measuring left ventricular mass, measurements of left ventricular mass made using this technique were compared with left ventricular weight in 10 mongrel dogs. Left ventricular myocardial volume was measured from five short-axis ehd-di...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 1986-07, Vol.8 (1), p.113-117
Main Authors: Keller, Andrew M., Peshock, Ronald M., Malloy, Craig R., Maximilian Buja, L., Nunnally, Ray, Parkey, Robert W., Willerson, James T.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cardiovascular system
Dogs
Heart Ventricles - anatomy & histology
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Spectroscopy
Medical sciences
Organ Size
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Space life sciences
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Summary:To examine the accuracy of nuclear magnetic resonance imaging in measuring left ventricular mass, measurements of left ventricular mass made using this technique were compared with left ventricular weight in 10 mongrel dogs. Left ventricular myocardial volume was measured from five short-axis ehd-diastolic images that spanned the left ventricle. Left ventricular mass was calculated from left ventricular myocardial volume and compared with the left ventricular weight determined after formalin immersion-fixation. Linear regression analysis yielded the following relation in grams: left ventricular mass determined using nuclear magnetic resonance imaging = (0.94) (left ventricular weight) + 9.1 (r = 0.98, SEE = 6.1 g). The small overestimation of left ventricular weight by nuclear magnetic resonance imaging was judged to be secondary to both difficulty with proper border definition and partial volume effects. Hence, this imaging technique can be used to obtain accurate measurements of left ventricular mass in dogs in vivo.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(86)80100-0