Segmental analysis of resting echocardiographic function and stress scintigraphic perfusion: Implications for myocardial viability

In 73 patients with coronary artery disease, we performed segmental analysis of resting two-dimensional echocardiography and stress thallium-201 single photon emission computed tomographic scintigraphy with 24-hour delayed imaging to test the hypotheses that (1) combined analysis of stress thallium-...

Full description

Saved in:
Bibliographic Details
Published in:The American heart journal 1995, Vol.129 (1), p.7-14
Main Authors: Foster, Elyse, O'Kelly, Brian, LaPidus, Andrew, Sandler, Dyan, Tucker, Kelly, Dae, Michael, Schiller, Nelson B., Botvinick, Elias H.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Cardiac Catheterization
Cardiovascular system
Chi-Square Distribution
Coronary Disease - diagnostic imaging
Echocardiography - instrumentation
Echocardiography - methods
Echocardiography - statistics & numerical data
Exercise Test - methods
Exercise Test - statistics & numerical data
Female
Heart - diagnostic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Radionuclide investigations
Rest
Retrospective Studies
Thallium Radioisotopes
Time Factors
Tissue Survival
Tomography, Emission-Computed, Single-Photon - methods
Tomography, Emission-Computed, Single-Photon - statistics & numerical data
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In 73 patients with coronary artery disease, we performed segmental analysis of resting two-dimensional echocardiography and stress thallium-201 single photon emission computed tomographic scintigraphy with 24-hour delayed imaging to test the hypotheses that (1) combined analysis of stress thallium-201 scintigraphy (with 24-hour redistribution) and echocardiography provides an evaluation of the viability of most myocardial segments; and (2) the severity of the scintigraphic perfusion abnormality in a given segment is equivalent to the severity of its echocardiographically determined functional impairment. Scintigraphy showed 14% of the 1168 segments analyzed to have fixed severe defects. Echocardiography showed 11% of the 1070 segments analyzed to be akinetic or dyskinetic. However, with combined analysis, only 62 (5%) segments showed no evidence of viability by either imaging technique. We conclude that in this group of patients, 95% of segments have evidence of viability by one of these two conventional imaging techniques.
ISSN:0002-8703
1097-6744
DOI:10.1016/0002-8703(95)90035-7