A novel mode of arbovirus transmission involving a nonviremic host

In nature, infected and uninfected arthropod vectors often feed together on an animal. In mimicking this scenario in the laboratory, uninfected vectors were found to acquire virus while cofeeding on the same host as infected vectors. However, the vertebrate host on which they fed did not develop det...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1987-08, Vol.237 (4816), p.775-777
Main Authors: Jones, Linda D., Davies, Clive R., Steele, Gordon M., Nuttall, Patricia A.
Format: Article
Language:English
Subjects:
Adult insects
Animals
Arachnid Vectors
Arbovirus diseases
Arbovirus Infections - transmission
Arboviruses
Arboviruses - isolation & purification
Biological and medical sciences
Biology
Blood
bunyaviridae
cobaye
cobayo
Cricetinae
Disease transmission
Epidemiology
Feeding Behavior
Female animals
Fundamental and applied biological sciences. Psychology
Guinea Pigs
Infections
Male animals
Medical research
Microbiology
Nymphs
rhipicephalus
Ticks
Ticks - microbiology
transmision de enfermedades
transmission des maladies
vecteur
vectores
vectors
Virology
Virus Replication
Viruses
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Summary:In nature, infected and uninfected arthropod vectors often feed together on an animal. In mimicking this scenario in the laboratory, uninfected vectors were found to acquire virus while cofeeding on the same host as infected vectors. However, the vertebrate host on which they fed did not develop detectable levels of virus in its blood. These observations were made with Thogoto virus, an influenza-like virus of medical and veterinary significance. Rhipicephalus appendiculatus ticks were used as the vector and guinea pigs as the vertebrate host. The results demonstrate that a vertebrate that is apparently refractory to infection by an arthropod-borne virus can still play an important role in the epidemiology of the virus, and they suggest a novel mode of arthopod-borne virus transmission.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.3616608