Economic Analysis of Alzheimer's Disease in Outpatients: Impact of Symptom Severity

To assess the economic burden of Alzheimer's disease (AD), we carried out a cross-sectional prevalence cost-of-illness study in France. Fifty-one probable AD patients (NINCDS-ADRDA) actually treated in ambulatory care were recruited in two university outpatient centers. Demographic, clinical (i...

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Bibliographic Details
Published in:International psychogeriatrics 1995-03, Vol.7 (1), p.115-122
Main Authors: Souêtre, Eric Jacques, Qing, Wen, Vigoureux, Isabel, Dartigues, Jean-François, Lozet, Helene, Lacomblez, Luciette, Derouesné, Christian
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alzheimer Disease - classification
Alzheimer Disease - economics
Alzheimer Disease - epidemiology
Alzheimer's Disease
Ambulatory care
Ambulatory Care - economics
Biological and medical sciences
Clinical Practice and Service Development
Cost of Illness
Costs
Cross-Sectional Studies
Economic analysis
Expenditures
Female
Financing, Government - economics
Financing, Personal - economics
Forecasting
France
France - epidemiology
Health Care Costs
Humans
Incidence
Male
Medical sciences
Mini-Mental State Examination
Miscellaneous
Outpatients
Public health. Hygiene
Public health. Hygiene-occupational medicine
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Summary:To assess the economic burden of Alzheimer's disease (AD), we carried out a cross-sectional prevalence cost-of-illness study in France. Fifty-one probable AD patients (NINCDS-ADRDA) actually treated in ambulatory care were recruited in two university outpatient centers. Demographic, clinical (including actual Mini-Mental State Examination scores), and economic data were collected by clinical investigators and trained interviewers. Total costs included actual expenditures such as direct medical costs and direct nonmedical costs, as well as indirect costs (loss of earnings due to loss of productivity). Cost valuation was based on the societal perspective using an opportunity costing approach. We found that indirect costs represented a significant portion of total costs (36%-40%). In terms of expenditures, patients and caregivers were found to bear the major part of AD total costs. We found a positive and significant correlation between disease severity and costs. Our findings support the hypothesis of a relationship between disease evolution and healthcare costs.
ISSN:1041-6102
1741-203X
DOI:10.1017/S1041610295001906