Benefits of adherence to anti-hypertensive drug therapy

Long-term adherence or compliance with anti-hypertensive drug therapy is poor. It has been estimated that within the first year of treatment 16–50% of hypertensives discontinue their anti-hypertensive medications. Even among those who remain on therapy long term, missed medication doses are common....

Full description

Saved in:
Bibliographic Details
Published in:European heart journal 1996-03, Vol.17 (suppl-A), p.16-20
Main Authors: Flack, J. M., Novikov, S. V., Ferrario, C. M.
Format: Article
Language:English
Subjects:
Adherence
Antihypertensive Agents - economics
Antihypertensive Agents - metabolism
Antihypertensive Agents - therapeutic use
Half-Life
Humans
hypertension
Patient Compliance
Randomized Controlled Trials as Topic
TOMHS
Treatment Outcome
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Long-term adherence or compliance with anti-hypertensive drug therapy is poor. It has been estimated that within the first year of treatment 16–50% of hypertensives discontinue their anti-hypertensive medications. Even among those who remain on therapy long term, missed medication doses are common. Epidemiological studies have shown that drug-treated hypertensives have higher blood pressures than age-, gender- and body mass index-matched normotensives. In addition, drugtreated hypertensive men and women who achieve blood pressure normalization are less likely to die over a 9·5-year period than those whose blood pressure remains elevated while taking anti-hypertensive drugs. Thus, one reason for less than optimal reduction of blood pressure-related cardiovascular-renal risk in drugtreated hypertensives is inadequate blood pressure lowering. Quantifiable excess risk has been documented even in the short term (
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/17.suppl_A.16