Conserved and variable elements in RNA genomes of potexviruses

• Published in: FEBS letters 1988-11, Vol.240 (1), p.33-40
• Main Authors: Skryabin, K.G., Morozov, S.Yu, Kraev, A.S., Rozanov, M.N., Chernov, B.K., Lukasheva, L.I., Atabekov, J.G.
• Format: Article
• Language: English
• Subjects: Amino Acid Sequence; Base Sequence; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Genes, Viral; Genes. Genome; Genome organization; Molecular and cellular biology; Molecular genetics; Molecular Sequence Data; Plant virus; Plant Viruses - genetics; Potexvirus; RNA, Viral; Sequence homology; Species Specificity; Viral Proteins - genetics
• ISSN: 0014-5793; 1873-3468
• DOI: 10.1016/0014-5793(88)80335-1

The nucleotide sequences of genomic RNAs and predicted amino acid sequences of two strains of potato virus X and white clover mosaic potexvirus were compared to each other, and the proteins of different plus-RNA-containing plant viruses. The predicted non-virion proteins of potexviruses have direct sequence homology and common structural peculiarities with those of several ‘Sindbis-like’ plant viruses. The most conserved amino acid sequences were found to be located in the polypeptide encoded by the long 5′-proximal open reading frame (ORF1). The putative polypeptide encoded by the ORF2 starting beyond the ORF1 stop codon is clearly related to the presumptive NTP-binding domain of the ORF1-coded polypeptide. These results suggest possible functions for all of the potexvirus proteins and also indicate that potexviruses have a genome organization which is considerably different from that of other plant viruses.