Input and Response Determinants of Visual Extinction: A Case Study

• Published in: Cortex 1996-12, Vol.32 (4), p.567-591
• Main Authors: Smania, N., Martini, M.C., Prior, M., Marzi, C.A.
• Format: Article
• Language: English
• Subjects: Brain Ischemia - pathology; Brain Ischemia - physiopathology; Humans; Male; Middle Aged; Neural Pathways - physiopathology; Visual Cortex - pathology; Visual Cortex - physiopathology
• ISSN: 0010-9452; 1973-8102
• DOI: 10.1016/S0010-9452(96)80032-3

We have studied a patient, CZ, with contralateral visual extinction due to a large ischaemic frontal-parietal-temporal lesion in the right hemisphere. We found that manipulation of intensity of the visual stimulus had little effect while an increase in eccentricity substantially increased extinction rate. An important factor was represented by the hemifield of stimulus presentation: when double stimuli were presented to the contralesional (left) hemifield, the leftmost stimulus was consistently extinguished while when stimuli were presented to the ipsilesional (right) hemifield, extinction was absent. Such effect was specific to hemifield rather than to head- and trunk-defined hemispace. Manipulation of response-related variables affected extinction to a large extent: In particular, the use of nonverbal responses diminished extinction considerably. This suggests that an important component of extinction may be represented by an impaired access of visual information to the left hemisphere. Finally, the RT results confirmed previous evidence of an ipsilesional attentional bias favouring, the rightmost stimuli both in the contralesional and in the ipsilesional hemifield.