Plugged liver biopsy in patients with impaired coagulation

Histology is of paramount importance in the investigation of hepatic disease but conventional percutaneous liver biopsy is contraindicated when coagulation is significantly impaired. We have used a modified percutaneous approach with plugging of the needle track in 100 patients with vitamin K-resist...

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Bibliographic Details
Published in:Digestive diseases and sciences 1989, Vol.34 (1), p.13-15
Main Authors: TOBIN, M. V, GILMORE, I. T
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle - methods
Blood Coagulation Disorders
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Liver - pathology
Liver Diseases - pathology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Other diseases. Semiology
Risk Factors
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Summary:Histology is of paramount importance in the investigation of hepatic disease but conventional percutaneous liver biopsy is contraindicated when coagulation is significantly impaired. We have used a modified percutaneous approach with plugging of the needle track in 100 patients with vitamin K-resistant prolongation of prothrombin time up to 12 sec above control values or platelet counts as low as 20 X 10(9)/liter. All were successful, and there were no serious complications. The technique is straightforward and is a feasible alternative to the more complex transvenous approach.
ISSN:0163-2116
1573-2568
DOI:10.1007/BF01536147