Dietary selenium repletion may reduce cancer incidence in people at high risk who live in areas with low soil selenium

Studies examining the relationship between dietary selenium intake and risk of various cancers have shown that low selenium intake is associated with higher cancer rates. A recent well-controlled intervention trial studied whether selenium supplementation can prevent cancer in subjects who have a hi...

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Bibliographic Details
Published in:Nutrition reviews 1997-07, Vol.55 (7), p.277-279
Main Authors: Fleet, J.C, Mayer, J
Format: Article
Language:English
Subjects:
Biological and medical sciences
CARCINOMA
CARCINOME
CLINICAL TRIALS
COMPLEMENT ALIMENTAIRE
CONTROL DE ENFERMEDADES
CONTROLE DE MALADIES
DIET
DIETA
Dietary supplements
DISEASE CONTROL
DISEASE PREVENTION
ENSAYOS CLINICOS
Enzymes
ESSAI CLINIQUE
Female
FEMME
HOMBRES
HOMME
Human physiology applied to population studies and life conditions. Human ecophysiology
Humans
INGESTION DE NUTRIENTES
INGESTION DE SUBSTANCES NUTRITIVES
LITERATURE REVIEWS
Male
Medical sciences
MEN
Minerals
MUJERES
Neoplasms - epidemiology
Neoplasms - prevention & control
NUTRIENT INTAKE
Nutrition
Nutritional survey. Food supply and nutritional requirement
PATIENTS
REGIME ALIMENTAIRE
Risk Factors
SELENIO
SELENIUM
Selenium - administration & dosage
Selenium - analysis
Selenium - therapeutic use
Skin cancer
Soil - analysis
Soils
SUPLEMENTOS
SUPPLEMENTS
WOMEN
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Description
Summary:Studies examining the relationship between dietary selenium intake and risk of various cancers have shown that low selenium intake is associated with higher cancer rates. A recent well-controlled intervention trial studied whether selenium supplementation can prevent cancer in subjects who have a history of skin cancer and live in areas of the United States with low soil selenium levels. Selenium supplementation did not reduce skin cancer rates, but the incidence of total, lung, colorectal, and prostate cancers was significantly reduced by the intervention. Although these data need confirmation, they suggest that adequate selenium intake is essential for cancer prevention
ISSN:0029-6643
1753-4887
DOI:10.1111/j.1753-4887.1997.tb01617.x