Cost‐effectiveness of inpatient and intensive outpatient treatment of rheumatoid arthritis. A randomized, controlled trial

Women with active rheumatoid arthritis who were judged to be in need of hospitalization were assigned at random to receive inpatient therapy (n = 35) or intensive outpatient therapy (n = 36). All relevant costs of treatment were measured. At 19 weeks, clinical outcomes, as summarized in a pooled ind...

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Bibliographic Details
Published in:Arthritis and rheumatism 1989-12, Vol.32 (12), p.1505-1514
Main Authors: Helewa, Antoine, Bombardier, Claire, Goldsmith, Charles H., Menchions, Bruce, Smythe, Hugh A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Ambulatory Care - economics
Analysis of Variance
Anti-Inflammatory Agents - therapeutic use
Arthritis, Rheumatoid - blood
Arthritis, Rheumatoid - drug therapy
Arthritis, Rheumatoid - physiopathology
Biological and medical sciences
Blood Sedimentation
Cost-Benefit Analysis
Diseases of the osteoarticular system
Female
Hospitalization - economics
Humans
Inflammatory joint diseases
Joints - physiopathology
Medical sciences
Middle Aged
Outcome and Process Assessment (Health Care)
Randomized Controlled Trials as Topic
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Summary:Women with active rheumatoid arthritis who were judged to be in need of hospitalization were assigned at random to receive inpatient therapy (n = 35) or intensive outpatient therapy (n = 36). All relevant costs of treatment were measured. At 19 weeks, clinical outcomes, as summarized in a pooled index, were significantly better in the inpatient group (pooled index units: inpatient 0.72, outpatient 0.25; F[1,69] = 10.9, P = 0.002). Inpatient therapy produced a sustained threefold increase in efficacy, at a 2.5‐fold increase in cost to society.
ISSN:0004-3591
1529-0131
DOI:10.1002/anr.1780321203