Silent Myocardial ischemia in Kawasaki disease : Evaluation of percutaneous transluminal coronary angioplasty by dobutamine stress testing

Myocardial ischemia and myocardial infarction are the most serious complications of coronary artery lesions in children with Kawasaki disease (KD). Therefore, early detection and treatment of myocardial ischemia in patients with KD is essential. We studied the effectiveness of percutaneous translumi...

Full description

Saved in:
Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1997-11, Vol.96 (10), p.3384-3389
Main Authors: OGAWA, S, FUKAZAWA, R, GENMA, Y, YAMAMOTO, M, OHKUBO, T, ZHANG, J, TAKECHI, N, KURAMOCHI, Y, HINO, Y, JIMBO, O, KATSUBE, Y, KAMISAGO, M
Format: Article
Language:English
Subjects:
Adolescent
Angioplasty, Balloon, Coronary
Biological and medical sciences
Body Surface Potential Mapping
Cardiotonic Agents
Child
Child, Preschool
Coronary Angiography
Dobutamine
Electrocardiography
Evaluation Studies as Topic
Exercise Test
Humans
Infant
Male
Medical sciences
Mucocutaneous Lymph Node Syndrome - complications
Myocardial Ischemia - diagnosis
Myocardial Ischemia - etiology
Myocardial Ischemia - therapy
Organophosphorus Compounds
Organotechnetium Compounds
Radiopharmaceuticals
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Tomography, Emission-Computed, Single-Photon
Ultrasonography, Interventional
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Myocardial ischemia and myocardial infarction are the most serious complications of coronary artery lesions in children with Kawasaki disease (KD). Therefore, early detection and treatment of myocardial ischemia in patients with KD is essential. We studied the effectiveness of percutaneous transluminal coronary angioplasty (PTCA) in patients with silent myocardial ischemia detected by dobutamine stress 99mTc myocardial scintigraphy (TMS), body surface mapping (BMS), and signal-averaged ECG late potentials (ELP). Eight of 76 asymptomatic patients with a coronary stenosis >25% and a positive dobutamine stress test were considered to have silent myocardial ischemia. All eight patients had >95% stenoses demonstrated by coronary angiography (CAG) just before PTCA. After PTCA, CAG showed that all of the coronary artery stenoses had been reduced to
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.96.10.3384