Effect of calcium carbonate on the compliance of an apatitic calcium phosphate bone cement

Clinical requirements for calcium phosphate bone cements were formulated in terms of the initial setting time, the final setting time, the cohesion time and the ultimate compressive strength. Three cement formulations were tested. The previously developed Biocement H was made of a powder containing...

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Bibliographic Details
Published in:Biomaterials 1997-12, Vol.18 (23), p.1535-1539
Main Authors: KHAIROUN, I, BOLTONG, M. G, DRIESSENS, F. C. M, PLANELL, J. A
Format: Article
Language:English
Subjects:
Apatites - chemistry
Biocompatible Materials - chemistry
Biological and medical sciences
Biomechanical Phenomena
Bone Cements - standards
Calcite
Calcium Carbonate - chemistry
Composition effects
Compressive strength
Medical sciences
Phosphate minerals
Powders
Precipitation (chemical)
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technology. Biomaterials. Equipments
Viscosity
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Summary:Clinical requirements for calcium phosphate bone cements were formulated in terms of the initial setting time, the final setting time, the cohesion time and the ultimate compressive strength. Three cement formulations were tested. The previously developed Biocement H was made of a powder containing alpha-tertiary calcium phosphate and precipitated hydroxyapatite. Biocement B2 powder was made by adding some CaCO3 to Biocement H, whereas Biocement B1 was made by adding some CaCO3 but with simultaneous adjustment of the amount of precipitated hydroxyapatite.The liquid/ powder ratio of the cement paste and the accelerator concentrations (percentage Na2HPO4) in cement liquid were varied. For Biocement H there was no combination of L/P ratio and percentage Na2HPO4 for which all clinical requirements were satisfied. However, there was an area of full compliance for Biocements B1 and B2, of which that for B1 was the largest. Therefore, Biocement B1 may be applied in clinical situations as those in orthopaedics, plastic and reconstructive surgery and oral and maxillofacial surgery, even when early contact with blood is inevitable.
ISSN:0142-9612
1878-5905
DOI:10.1016/s0142-9612(97)00096-3