Treatment of Dairy Cows with Recombinant Bovine Somatotropin: Genetic and Phenotypic Aspects

Thirty-four multiparous and primiparous Holstein cows were utilized to examine the association between the response to long-term administration of recombinant bovine somatotropin and the cow's phenotypic and genetic production potential. Cows representing a range of phenotypic and genetic produ...

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Bibliographic Details
Published in:Journal of dairy science 1990-01, Vol.73 (1), p.181-190
Main Authors: Leitch, Helen W., Burnside, Edward B., McBride, Brian W.
Format: Article
Language:English
Subjects:
Analysis of Variance
Animals
BOVIN LAITIER
Cattle - genetics
Cattle - physiology
COWS
DAIRY CATTLE
Female
FENOTIPOS
GANADO DE LECHE
genetics
Growth Hormone - pharmacology
HORMONAS PITUITARIAS
HORMONE HYPOPHYSAIRE
Lactation - drug effects
Lactation - genetics
Least-Squares Analysis
Milk - analysis
Milk - drug effects
MILK PRODUCTION
PHENOTYPE
PHENOTYPES
PITUITARY HORMONES
POTENCIAL DE PRODUCCION
POTENTIEL DE PRODUCTION
Pregnancy
PRODUCCION LECHERA
PRODUCTION LAITIERE
PRODUCTION POTENTIAL
Recombinant Proteins - pharmacology
Regression Analysis
somatotropin
VACA
VACHE
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Summary:Thirty-four multiparous and primiparous Holstein cows were utilized to examine the association between the response to long-term administration of recombinant bovine somatotropin and the cow's phenotypic and genetic production potential. Cows representing a range of phenotypic and genetic production potentials were assigned to one of four treatment groups: 0, 12.5, 25.0, or 50.0mg recombinant bovine somatotropin daily. They were injected daily for 266 d beginning on d 24 to 35 postpartum. Pretreatment milk and fat yields were used to predict daily yields over the lactation and allowed treatment groups to serve as their own controls. Actual minus predicted yield estimated the response to treatment for milk, fat, and FCM for each cow. Milk composition (fat, protein, and lactose percentage) was not significantly affected by treatment. Response in yield for milk, fat, and FCM was significant during the treatment period (266 d). Milk yield increased by 18.5, 19.9, and 21.4%; fat yield increased by 13.4, 20.3, and 18.1%; and FCM increased by 16.3%, 19.7%, and 21.1% after receipt of 12.5, 25.0 and 50.0mg recombinant bovine somatotropin, respectively. Differences in response were not significant. The dramatic effect recombinant bovine somatotropin has on production requires that alternative approaches be adopted in the future for accurate genetic evaluation of sires and dams if somatotropin is discriminately used in the national herd.
ISSN:0022-0302
1525-3198
DOI:10.3168/jds.S0022-0302(90)78662-6