Reversible Ischemia in Hippocampal Areas by Retrograde Cerebral Circulation Surgery for Thoracic Aortic Aneurysm with Tc-99m ECD Brain SPECT

Because hippocampal neurons are quite vulnerable to the anoxic brain injury that sometimes occurs in aortic arch surgery in humans, hippocampal ischemia should be a sensitive indicator of global cerebral ischemia. It was concluded that the hypothermic retrograde cerebral circulation technique for ao...

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Bibliographic Details
Published in:Clinical nuclear medicine 1998-02, Vol.23 (2), p.86-89
Main Authors: HAYASHIDA, KOHEI, TAKAMOTO, SHINICHI, HIROSE, YOSHIAKI, KUME, NORIHIKO, HASHIMOTO, HIROYUKI, CHO, IHNHO, NISHIMURA, TSUNEHIKO
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Anesthesia
Anesthesia depending on type of surgery
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Aortic Aneurysm, Thoracic - surgery
Biological and medical sciences
Brain - diagnostic imaging
Brain Ischemia - diagnostic imaging
Brain Ischemia - etiology
Cerebrovascular Circulation
Cysteine - analogs & derivatives
Female
Hippocampus - blood supply
Hippocampus - diagnostic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Nervous system
Organotechnetium Compounds
Radionuclide investigations
Radiopharmaceuticals
Thoracic and cardiovascular surgery. Cardiopulmonary bypass
Tomography, Emission-Computed, Single-Photon
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Summary:Because hippocampal neurons are quite vulnerable to the anoxic brain injury that sometimes occurs in aortic arch surgery in humans, hippocampal ischemia should be a sensitive indicator of global cerebral ischemia. It was concluded that the hypothermic retrograde cerebral circulation technique for aortic arch surgery could not only be performed safely with respect to the brain, but could also increase blood flow to the hippocampal areas, probably as a result of restoration of blood flow in the thoracic aorta.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199802000-00005