A population-based study of abdominal wall defects in South Australia and Western Australia

The purpose of this study was to determine the prevalence, clinical characteristics, prenatal diagnosis and occurrence of other birth defects with abdominal wall defects in births and terminations of pregnancy in South Australia (SA) and Western Australia (WA) over the period 1980–90. Cases of gastr...

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Bibliographic Details
Published in:Paediatric and perinatal epidemiology 1998-04, Vol.12 (2), p.136-151
Main Authors: Byron-Scott, Rosemary, Haan, Eric, Chan, Annabelle, Bower, Carol, Scott, Heather, Clark, Kathryn
Format: Article
Language:English
Subjects:
Abdominal Muscles - abnormalities
Adult
Bladder Exstrophy - epidemiology
Confidence Intervals
Congenital Abnormalities - epidemiology
Female
Hernia, Umbilical - epidemiology
Humans
Infant, Newborn
Maternal Age
Odds Ratio
Poisson Distribution
Pregnancy
Prenatal Diagnosis - statistics & numerical data
Prevalence
Registries - statistics & numerical data
Regression Analysis
Risk Factors
South Australia - epidemiology
Umbilical Cord - abnormalities
Western Australia - epidemiology
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Summary:The purpose of this study was to determine the prevalence, clinical characteristics, prenatal diagnosis and occurrence of other birth defects with abdominal wall defects in births and terminations of pregnancy in South Australia (SA) and Western Australia (WA) over the period 1980–90. Cases of gastroschisis, exomphalos, bladder exstrophy, cloacal exstrophy and body stalk anomaly were ascertained from the WA Birth Defects Registry (1980–90) and the SA Birth Defects Register (1986–90). The registers are comparable population‐based data collections with information on livebirths and stillbirths of at least 400 g birthweight or 20 weeks’ gestation, and terminations of pregnancy for fetal abnormality. The prevalence of gastroschisis was 1.65/10 000 births (59 cases) and of exomphalos 2.90/10 000 births (104 cases). There was no significant difference in prevalence of exomphalos or gastroschisis between SA and WA for the years 1986–90. However, if data from WA for the years 1980–85 were included, SA had a significantly higher prevalence of exomphalos (prevalence ratio 1.71, confidence interval [CI] 1.16–2.55), although not of gastroschisis (prevalence ratio 1.35, CI 0.79–2.32). Exomphalos was significantly more common in mothers 
ISSN:0269-5022
1365-3016
DOI:10.1046/j.1365-3016.1998.00090.x