Acetic acid improves identification of remnant islands of Barrett's epithelium after endoscopic therapy

Background: Instillation of acetic acid onto the uterine cervix at colposcopy has been used for many years to highlight dysplastic areas and thereby enhance the ability to obtain targeted biopsy specimens. As part of an ongoing trial of multipolar electrocoagulation for Barrett's esophagus, we...

Full description

Saved in:
Bibliographic Details
Published in:Gastrointestinal endoscopy 1998-06, Vol.47 (6), p.512-515
Main Authors: Guelrud, Moises, Herrera, Idamys
Format: Article
Language:English
Subjects:
Acetic Acid
Barrett Esophagus - pathology
Barrett Esophagus - surgery
Biological and medical sciences
Electrocoagulation
Epithelium - pathology
Esophagoscopy - methods
Esophagus
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Indicators and Reagents - administration & dosage
Medical sciences
Mucous Membrane - pathology
Other diseases. Semiology
Pilot Projects
Postoperative Period
Prospective Studies
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Instillation of acetic acid onto the uterine cervix at colposcopy has been used for many years to highlight dysplastic areas and thereby enhance the ability to obtain targeted biopsy specimens. As part of an ongoing trial of multipolar electrocoagulation for Barrett's esophagus, we sought to develop a simple technique to identify small islands of residual specialized columnar epithelium after treatment. Methods: In 21 consecutive patients, 5 to 10 mL of 1.5% acetic acid was sprayed onto the distal esophagus using a spray catheter, followed immediately by spraying 50 mL of tap water. Results: Initially, a whitish coloration developed in both esophageal and gastric epithelia. After 2 to 3 minutes, the esophageal squamous mucosa remained white but the columnar epithelium became reddish. Remnant islands of Barrett's epithelium were outlined by a white rim. Conclusion: Acetic acid instillation enhances the ability to detect small or indistinguishable remnant islands of columnar epithelium after endoscopic treatment of Barrett's esophagus. This method is safe, rapid, and inexpensive.
ISSN:0016-5107
1097-6779
DOI:10.1016/S0016-5107(98)70253-6