Intravenous glucose tolerance test—derived glucose effectiveness in strength-trained humans

• Published in: Metabolism, clinical and experimental clinical and experimental, 1998-07, Vol.47 (7), p.874-877
• Main Authors: Fujitani, Junzo, Higaki, Yasuki, Kagawa, Toshiko, Sakamoto, Makoto, Kiyonaga, Akira, Shindo, Munehiro, Taniguchi, Ataru, Nakai, Yoshikatu, Tokuyama, Kumpei, Tanaka, Hiroaki
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Blood Glucose - metabolism; Body Composition - physiology; Exercise Test; Functional investigation of endocrine glands and genital system; Glucose Tolerance Test; Humans; Insulin - blood; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Models, Biological; Oxygen Consumption; Physical Endurance - physiology; Physical Fitness - physiology; Weight Lifting - physiology
• ISSN: 0026-0495; 1532-8600
• DOI: 10.1016/S0026-0495(98)90129-9

The effect of long-term strenuous resistance training on glucose effectiveness (SG) was examined by comparing 11 strength-trained and 20 sedentary males by a minimal model approach. Lean body mass (LBM) was measured by hydrostatic weighing. The LBM in strength-trained subjects (65.7 ± 3.1 kg) was significantly larger than in sedentary subjects (56.6 ± 1.2 kg, P < .01). The glucose disappearance constant ([KG] 3.07% ± 0.45% · min −1) and insulin sensitivity ([SI] 17.5 ± 2.0 × 10 −5 · min −1 · pmol/L −1) in strength-trained subjects were significantly higher than in sedentary subjects (2.06% ± 0.14% · min −1 and 10.3 ± 1.2 × 10 −5 · min −1 · pmol/L −1, P < .05). SG in strength-trained subjects (0.024 ± 0.003 min −1) was significantly higher than in sedentary subjects (0.018 ± 0.001 min −1, P < .05). These results thus suggest that the improved glucose tolerance in strength-trained subjects was due to increased SG and SI.