Metastatic Calcification in a Patient with Malignant Parathyroid Carcinoma: Correlation of Clinical, Surgical, Radiographic, and Scintigraphic Findings

A patient whose bone scan showed features typical of a "superscan," having extensive pulmonary, cardiac, and renal calcifications is described. Metastatic parathyroid carcinoma with renal insufficiency and phosphate retention are cited as the cause. Early diagnosis and surgical extirpation...

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Bibliographic Details
Published in:Clinical nuclear medicine 1990-10, Vol.15 (10), p.692-696
Main Authors: DAVIDSON, ROBERT M, DHEKNE, RAMESH D, MOORE, WARREN H, BUTLER, DONALD B
Format: Article
Language:English
Subjects:
Bone Neoplasms - diagnosis
Bone Neoplasms - secondary
Calcinosis - diagnosis
Calcinosis - etiology
Carcinoma - diagnosis
Carcinoma - secondary
Diagnostic Imaging
Humans
Male
Middle Aged
Parathyroid Neoplasms - pathology
Soft Tissue Neoplasms - diagnosis
Soft Tissue Neoplasms - secondary
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Summary:A patient whose bone scan showed features typical of a "superscan," having extensive pulmonary, cardiac, and renal calcifications is described. Metastatic parathyroid carcinoma with renal insufficiency and phosphate retention are cited as the cause. Early diagnosis and surgical extirpation offer the best chance for cure or palliation. Pitfalls of plain film radiography in identifying metastases and pathologic soft tissue calcifications in the setting of severe hyperparathyroidism are discussed, and the advantages of functional radionuclide imaging assessments are emphasized.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199015100-00007