Brain MRI in obsessive-compulsive disorder

Magnetic resonance imaging (MRI) brain scans were performed on 12 patients with obsessive-compulsive disorder and 12 healthy controls. Measurements of the area of the head of the caudate nucleus, cingulate gyrus thickness, intracaudate/frontal horn ratio, and area of the corpus callosum did not diff...

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Bibliographic Details
Published in:Psychiatry research 1991, Vol.36 (1), p.45-49
Main Authors: Kellner, Charles H., Jolley, Robert R., Holgate, Richard C., Austin, Linda, Lydiard, R.Bruce, Laraia, Michele, Ballenger, James C.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Aged
Biological and medical sciences
Brain - pathology
Brain Mapping
caudate nucleus
Caudate Nucleus - pathology
Corpus Callosum - pathology
Female
Gyrus Cinguli - pathology
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Neurocognitive Disorders - diagnosis
Neurocognitive Disorders - pathology
Neurocognitive Disorders - psychology
obsessive-compulsive disorder
Obsessive-Compulsive Disorder - diagnosis
Obsessive-Compulsive Disorder - pathology
Obsessive-Compulsive Disorder - psychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
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Summary:Magnetic resonance imaging (MRI) brain scans were performed on 12 patients with obsessive-compulsive disorder and 12 healthy controls. Measurements of the area of the head of the caudate nucleus, cingulate gyrus thickness, intracaudate/frontal horn ratio, and area of the corpus callosum did not differ between the two groups. These limited data do not support the presence of a consistent gross brain structural abnormality in obsessive-compulsive disorder. Further studies using other anatomic measurements and other brain structural imaging techniques are warranted.
ISSN:0165-1781
1872-7123
DOI:10.1016/0165-1781(91)90116-7