Photosensitivity testing in children

• Published in: Journal of the American Academy of Dermatology 2010-12, Vol.63 (6), p.1019-1025
• Main Authors: ten Berge, Onno, MD, Sigurdsson, Vigfus, MD, PhD, Bruijnzeel-Koomen, Carla A.F.M., MD, PhD, van Weelden, Huib, MSc, Pasmans, Suzanne G.M.A., MD, PhD
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Biological and medical sciences; children; Dermatitis, Atopic - diagnosis; Dermatitis, Atopic - epidemiology; Dermatology; Disease Progression; Female; Follow-Up Studies; General aspects; Humans; Male; Medical sciences; photodermatosis; photosensitivity; Photosensitivity Disorders - diagnosis; Photosensitivity Disorders - epidemiology; phototest; Prevalence; Protoporphyria, Erythropoietic - diagnosis; Protoporphyria, Erythropoietic - epidemiology; Radiation Dosage; Retrospective Studies; Skin involvement in other diseases. Miscellaneous. General aspects; Skin Tests - methods; Skin Tests - statistics & numerical data; ultraviolet A; ultraviolet B; Ultraviolet Rays - adverse effects; visible light; Young Adult
• ISSN: 0190-9622; 1097-6787
• DOI: 10.1016/j.jaad.2009.12.032

Background Phototesting is an important diagnostic tool to objectify light-related symptoms. Data on phototesting procedures in children are scarce. Objective The aim of this study was to evaluate phototest results in photosensitivity disorders in children. Methods The phototest procedures are described. All children phototested in our department between 1995 and 2007 were included in this retrospective study. Children given the diagnosis of polymorphic light eruption (PLE) were selected for follow-up. Results A total of 92 children (39 boys and 53 girls, age range 4-16 years) were successfully phototested. A photosensitivity disorder was confirmed in 56 children (61%, 24 boys and 32 girls). PLE was diagnosed in 39%, photosensitivity associated with atopic dermatitis in 23%, and erythropoietic protoporphyria in 23%. Other diagnoses were less common. Ten children with PLE were followed up for at least 5 years. Seven reported their photosensitivity had not changed over time, in two cases it had diminished, and in one patient the photosensitivity had disappeared. Limitations Retrospective study design is a limitation. Conclusion Phototesting in children is feasible when performed in a case- and child-dependent manner. PLE was the most prevalent diagnosis in our series followed by photosensitivity in atopic dermatitis.