Cardiac output and central volume as determined by dye dilution curves; resting values in normal subjects and patients with cardiovascular disease

Dye dilution curves determined by the method of Hamilton have been obtained from a series of normal subjects and from a group of patients with various types of cardiovascular disorders. Cardiac indices calculated from these curves revealed expected values. Central volume, believed to be an index of...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1955-03, Vol.11 (3), p.447-455
Main Authors: KATTUS, A A, RIVIN, A U, COHEN, A, SOFIO, G S
Format: Article
Language:English
Subjects:
Blood Volume
Blood Volume Determination
Cardiac Output
Cardiovascular Diseases - physiology
Cardiovascular Physiological Phenomena
Coloring Agents
Heart
Humans
Old Medline
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Summary:Dye dilution curves determined by the method of Hamilton have been obtained from a series of normal subjects and from a group of patients with various types of cardiovascular disorders. Cardiac indices calculated from these curves revealed expected values. Central volume, believed to be an index of pulmonary blood volume, was calculated from the slopes of the down strokes of the curves. Central volume indices in normal subjects averaged 0.590 liters. Central volume in patients with heart disease was frequently normal or less than normal. Only cor pulmonale patients with high output had central volumes significantly greater than normal.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.11.3.447