Antibiotic prophylaxis in the placement of totally implanted central venous access ports

Abstract Background Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP) has not been studied. This retrospective review compared the rate of catheter-related infections (CRIs) with and without perioperative antibiotics. Methods This was a single-center study that...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of surgery 2010-12, Vol.200 (6), p.719-723
Main Authors: Scaife, Courtney L., M.D, Gross, Molly E., M.D, Mone, Mary C., R.N., B.S.E, Hansen, Heidi J, Litz, Codi L, Nelson, Edward T., B.A, Anderson, Clayton J., B.A, Wagner, Graham, B.A, Gawlick, Ute, M.D., Ph.D, Nelson, Edward W., M.D
Format: Article
Language:English
Subjects:
Age
Antibacterial agents
Antibiotic Prophylaxis
Antibiotics
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antineoplastic Agents - administration & dosage
Biological and medical sciences
Body mass index
Bone surgery
Cancer
Catheter-related infections
Catheter-Related Infections - prevention & control
Catheterization, Central Venous
Catheters
Catheters, Indwelling
Central venous access ports
Chemotherapy
Demographics
Demography
Diabetes
Dosage
Female
General aspects
Humans
Infections
Jugular Veins
Male
Medical instruments
Medical sciences
Middle Aged
Nosocomial infections
Oncology
Patients
Pharmacology. Drug treatments
Placement
Port-a-cath
Ports
Prevention and actions
Prophylactic antibiotics
Prophylaxis
Public health. Hygiene
Public health. Hygiene-occupational medicine
Skin
Subclavian Vein
Surgeons
Surgery
Transplants & implants
Tunneled infusion device
Veins & arteries
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP) has not been studied. This retrospective review compared the rate of catheter-related infections (CRIs) with and without perioperative antibiotics. Methods This was a single-center study that compared patients treated with and without a single dose of antibiotics during CVAP placement. CRIs were defined as a patient treated with antibiotics for port site induration, positive blood cultures, or suspicion of infection that led to port removal within 30 days of placement. Results CVAP were placed in 459 patients, 103 of whom (22.4%) received antibiotic prophylaxis. Surgical technique and patient demographics were similar to those patients not receiving antibiotics (356). All 9 (2%) CRIs occurred in the non-prophylactic antibiotic group ( P = .218), with 5 infections resulting in port removal. Conclusions Single-dose perioperative antibiotics may decrease CVAP infection rates and should be studied further in a prospective randomized trial.
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2010.07.023