Cardiac effects of antiretroviral therapy in HIV-negative infants born to HIV-positive mothers: NHLBI CHAART-1 (National Heart, Lung, and Blood Institute Cardiovascular Status of HAART Therapy in HIV-Exposed Infants and Children cohort study)

The aim of this study was to investigate the possible effects of antiretroviral therapy (ART) in utero on cardiac development and function in human immunodeficiency virus (HIV)-negative children. ART reduces vertical HIV transmission. Long-term cardiotoxicity after in utero exposure to ART is unknow...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2011-01, Vol.57 (1), p.76-85
Main Authors: Lipshultz, Steven E, Shearer, William T, Thompson, Bruce, Rich, Kenneth C, Cheng, Irene, Orav, E John, Kumar, Sulekha, Pignatelli, Ricardo H, Bezold, Louis I, LaRussa, Philip, Starc, Thomas J, Glickstein, Julie S, O'Brien, Sharon, Cooper, Ellen R, Wilkinson, James D, Miller, Tracie L, Colan, Steven D
Format: Article
Language:English
Subjects:
Adult
Age
Anti-Retroviral Agents - adverse effects
Anti-Retroviral Agents - therapeutic use
Antiretroviral Therapy, Highly Active - adverse effects
Cardiology
Cardiovascular disease
Child, Preschool
Drug therapy
Ethnicity
Female
Follow-Up Studies
Heart
Heart - drug effects
Heart - embryology
HIV
HIV - immunology
HIV Seropositivity - drug therapy
Human immunodeficiency virus
Humans
Infant
Infant, Newborn
Infectious Disease Transmission, Vertical
Lentivirus
Male
Maternal Exposure - adverse effects
Pregnancy
Pregnancy Complications, Infectious - drug therapy
Prospective Studies
Retroviridae
Risk Factors
Statistical methods
Ultrasonic imaging
Ventricular Function, Left - drug effects
Womens health
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