Fetal hemoglobin in the diagnosis of neonatal subarachnoid hemorrhage

Intracranial hemorrhage is a leading cause of mortality and morbidity in newborn infants, particularly those born prematurely.1-8 Major intracranial hemorrhage in the preterm infant is usually intraventricular.3-6 Although intraventricular hemorrhage is a common autopsy finding, it may be difficult...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 1976-11, Vol.58 (5), p.751-754
Main Authors: Chaplin, E R, Schlueter, M A, Phibbs, R H, Kitterman, J A, Tooley, W H
Format: Article
Language:English
Subjects:
Blood
Blood Transfusion
Cerebral Hemorrhage - blood
Cerebrospinal Fluid - analysis
Diagnosis, Differential
Enterocolitis, Pseudomembranous - complications
Fetal Hemoglobin - analysis
Heart Defects, Congenital - complications
Humans
Hyaline Membrane Disease - complications
Hydrocephalus - blood
Hydrogen-Ion Concentration
Infant, Newborn
Infant, Newborn, Diseases - blood
Subarachnoid Hemorrhage - blood
Subarachnoid Hemorrhage - complications
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Intracranial hemorrhage is a leading cause of mortality and morbidity in newborn infants, particularly those born prematurely.1-8 Major intracranial hemorrhage in the preterm infant is usually intraventricular.3-6 Although intraventricular hemorrhage is a common autopsy finding, it may be difficult to diagnose before death because its early signs are also often associated with cardiopulmonary disease.3-7 Thus, particularly in prematurely born infants with severe hyaline membrane disease, there may be no pathognomonic sign of intracranial bleeding and often only a presumptive clinical diagnosis can be made. Laboratory diagnosis based on bloody spinal fluid may also be misleading, since the blood in the spinal fluid could be the result of either a traumatic lumbar puncture or preexisting subarachnoid blood.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.58.5.751