Correlation of scintigraphy with short interval autopsy in malignant focal liver disease. A study of 59 cases

The accuracy of scintigraphy in focal liver disease was evaluated by comparing the scintigraphic and autopsy findings in 59 patients. The interval between scintigraphy and autopsy was not more than a few weeks. The overall agreement rate was 49 in 59 (83%), with four out of 26 (15%) false positive a...

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Bibliographic Details
Published in:Cancer 1977-01, Vol.39 (1), p.172-177
Main Authors: Ruiter, Dirk J., Byck, Walter, Pauwels, Ernest K. J., Taconis, Wybren K., Spaander, Piet Jan
Format: Article
Language:English
Subjects:
Adult
Autopsy
Evaluation Studies as Topic
False Negative Reactions
False Positive Reactions
Female
Humans
Liver Neoplasms - diagnosis
Liver Neoplasms - pathology
Male
Middle Aged
Neoplasm Metastasis
Organ Size
Radionuclide Imaging
Time Factors
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Summary:The accuracy of scintigraphy in focal liver disease was evaluated by comparing the scintigraphic and autopsy findings in 59 patients. The interval between scintigraphy and autopsy was not more than a few weeks. The overall agreement rate was 49 in 59 (83%), with four out of 26 (15%) false positive and six out of 33 (18%) false negative reports. Defects smaller than 2 ½ cm were the principal source of false negative reports. The accuracy of interpretation in cases with liver weights up to 2000 g was significantly (P < 0.025) lower than for higher weights. Detection of a single focal lesion by scintigraphy was found to be unreliable (only two out of 13 correct). Estimation of spleen weights by scintigraphy was disappointing. Liver weight estimates were somewhat more satisfactory.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197701)39:1<172::AID-CNCR2820390128>3.0.CO;2-V