Equine acquired multiple acyl-CoA dehydrogenase deficiency (MADD) in 14 horses associated with ingestion of Maple leaves (Acer pseudoplatanus) covered with European tar spot (Rhytisma acerinum)

This case-series describes fourteen horses suspected of equine acquired multiple acyl-CoA dehydrogenase deficiency (MADD) also known as atypical myopathy of which seven cases were confirmed biochemically with all horses having had access to leaves of the Maple tree (Acer pseudoplatanus) covered with...

Full description

Saved in:
Bibliographic Details
Published in:Molecular genetics and metabolism 2010-10, Vol.101 (2-3), p.289-291
Main Authors: van der Kolk, J.H., Wijnberg, I.D., Westermann, C.M., Dorland, L., de Sain-van der Velden, M.G.M., Kranenburg, L.C., Duran, M., Dijkstra, J.A., van der Lugt, J.J., Wanders, R.J.A., Gruys, E.
Format: Article
Language:English
Subjects:
Acer
Acer pseudoplatanus
Animals
Ascomycota
Atypical myopathy
Carboxylic Acids - urine
Carnitine - analogs & derivatives
Carnitine - urine
Equine
Female
Foodborne Diseases - veterinary
Glycine - urine
Horse Diseases - enzymology
Horse Diseases - urine
Horses
MADD
Male
Maple
Multiple Acyl Coenzyme A Dehydrogenase Deficiency - veterinary
Plant Diseases - microbiology
Plant Leaves
Rhytisma acerinum
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This case-series describes fourteen horses suspected of equine acquired multiple acyl-CoA dehydrogenase deficiency (MADD) also known as atypical myopathy of which seven cases were confirmed biochemically with all horses having had access to leaves of the Maple tree (Acer pseudoplatanus) covered with European tar spot (Rhytisma acerinum). Assessment of organic acids, glycine conjugates, and acylcarnitines in urine was regarded as gold standard in the biochemical diagnosis of equine acquired multiple acyl-CoA dehydrogenase deficiency.
ISSN:1096-7192
1096-7206
DOI:10.1016/j.ymgme.2010.06.019