Internal Exposure, Effect Monitoring, and Lung Function in Welders After Acute Short-Term Exposure to Welding Fumes From Different Welding Processes

Objective: In this study, the effect of short-term exposure to welding fumes emitted by different welding techniques on workers was investigated. Methods: In a 3-fold crossover study, six welders used three different welding techniques for 3 hours. Before and after welding, blood and urine samples w...

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Bibliographic Details
Published in:Journal of occupational and environmental medicine 2010-09, Vol.52 (9), p.887-892
Main Authors: Brand, Peter, Gube, Monika, Gerards, Kerstin, Bertram, Jens, Kaminski, Heinz, John, Astrid Christiane, Kuhlbusch, Thomas, Wiemann, Martin, Eisenbeis, Christian, Winkler, Reinhard, Kraus, Thomas
Format: Article
Language:English
Subjects:
Adult
Air Pollutants, Occupational - toxicity
Biological and medical sciences
Breath Tests
Chemical and industrial products toxicology. Toxic occupational diseases
Chromium - blood
Chromium - urine
Cross-Over Studies
Environmental Monitoring
Gas, fumes
Human exposure
Humans
Iron - blood
Iron - metabolism
Lungs
Male
Measurement
Medical sciences
Middle Aged
Nickel - blood
Nickel - urine
Nitrates - analysis
Nitrites - analysis
Occupational Exposure - adverse effects
Occupational Exposure - analysis
Occupational health
Original Article
Osteopontin - blood
Respiratory Function Tests
Respiratory Physiological Phenomena
Studies
Toxicology
Tyrosine - analogs & derivatives
Tyrosine - analysis
Welding
Welding - methods
Young Adult
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Summary:Objective: In this study, the effect of short-term exposure to welding fumes emitted by different welding techniques on workers was investigated. Methods: In a 3-fold crossover study, six welders used three different welding techniques for 3 hours. Before and after welding, blood and urine samples were collected to perform biomonitoring of metals. Breath condensate was collected to assess inflammatory reactions, and lung function measurements were performed. Results: Welding led to a significant increase of chromium and nickel in blood and urine and of nitrate and nitrite in exhaled breath condensate. These increases were higher for manual metal arc welding with alloyed material (MAW-a). Several lung function parameters decreased after welding. This decrease was significantly higher after MAW-a. Conclusions: In respect to biological effects, MAW-a seems to be more important than other welding techniques.
ISSN:1076-2752
1536-5948
DOI:10.1097/JOM.0b013e3181f09077