Seroepidemiologic Studies during a Simultaneous Epidemic of Infection with El Tor Ogawa and Classical Inaba Vibrio cholerae

A total of 247 family contacts of patients with El Tor Ogawa Vibrio cholerae and 73 family contacts of patients with classical Inaba V. cholerae were studied during a simultaneous epidemic of both biotypes in Chittagong, East Pakistan, in 1968-1969. There was a distinctly different pattern of infect...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of infectious diseases 1970-05, Vol.121 (Supplement), p.S17-S24
Main Authors: Bart, Kenneth J., Huq, Zahidul, Khan, Moslemuddin, Mosley, Wiley H., Nuruzzaman, Md, Golam Kibriya, A. K. M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age distribution
Age Factors
Age groups
Agglutination Tests
Antibodies
Bacteriological Techniques
Child
Child, Preschool
Cholera
Cholera - blood
Cholera - diagnosis
Cholera - epidemiology
Cholera - immunology
Epidemics
Epidemiology
Family
Female
Hospitalization
Humans
Infant
Infections
Infectious diseases
Male
Pakistan
Rectum - microbiology
Research and development laboratories
Session I: Epidemiologic Studies, Vaccine Trials, and Immune Response
Sex Factors
Species Specificity
Vibrio
Vibrio - immunology
Vibrio cholerae
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A total of 247 family contacts of patients with El Tor Ogawa Vibrio cholerae and 73 family contacts of patients with classical Inaba V. cholerae were studied during a simultaneous epidemic of both biotypes in Chittagong, East Pakistan, in 1968-1969. There was a distinctly different pattern of infection in family contacts. The infection-to-case ratio in El Tor Ogawa contacts was 36:1, compared with 4:1 for the classical Inaba family contacts. Even though the overall infection rates among family contacts were the same for both biotypes (46%), those contacts infected with El Tor Ogawa had a frequency of secondary hospitalized cases that was 8 times lower. The extrapolation of the hospital case rate to the incidence and prevalence of cholera infection in the community must take into consideration both the biotype and serotype of the infecting vibrio. Bacteriologic or serologic methods alone were not adequate to detect infections of either biotype. Combined usage of these techniques is recommended.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/121.Supplement.S17