What aspects of social network are protective for dementia? Not the quantity but the quality of social interactions is protective up to 15 years later

• Published in: Psychosomatic medicine 2010-11, Vol.72 (9), p.905-911
• Main Authors: Amieva, Hélène, Stoykova, Ralitsa, Matharan, Fanny, Helmer, Catherine, Antonucci, Toni C, Dartigues, Jean-François
• Format: Article
• Language: English
• Subjects: Activities of Daily Living; Aged; Alzheimer Disease - diagnosis; Alzheimer Disease - prevention & control; Alzheimer Disease - psychology; Alzheimer's disease; Causality; Dementia; Dementia - diagnosis; Dementia - prevention & control; Dementia - psychology; Female; Humans; Interpersonal Relations; Longitudinal Studies; Male; Morbidity; Older people; Outcome Assessment (Health Care); Personal Satisfaction; Prospective Studies; Psychosomatic medicine; Quality of Life; Reciprocity; Risk assessment; Risk Factors; Social networks; Social Support; Surveys and Questionnaires
• ISSN: 0033-3174; 1534-7796
• DOI: 10.1097/PSY.0b013e3181f5e121

To test the association between several social networks variables reflecting both structural characteristics and quality of relationships with the risk of dementia and Alzheimer's disease 5 and up to 15 years later. The study sample is gathered from the Paquid cohort, a French population-based study of 3,777 elderly people evaluated at baseline and regularly revisited during a 15-year interval. The sample consisted of 2,089 subjects who completed the social network questionnaire and were free of dementia at the time of enrollment and also at the next two follow-ups to minimize the problem of reverse causality. The questionnaire collected at baseline included marital status, number of ties, nature of social network, satisfaction, perception of being understood/misunderstood, and reciprocity in relationships. The incident cases of dementia considered were those diagnosed at 5-year and subsequent follow-ups, resulting in 461 dementia and 373 Alzheimer's disease cases. The multivariate Cox model, including the six social network variables and adjusted for numerous potential confounders, showed significant associations with satisfaction and reciprocity in relationships. Participants who felt satisfied with their relations had a 23% reduced dementia risk. Participants who reported that they received more support than they gave over their lifetime had a 55% and 53% reduced risk for dementia and Alzheimer's disease, respectively. The only variables associated with subsequent dementia or Alzheimer's disease were those reflecting the quality of relationships. The delay between social network assessment and dementia diagnosis was from 5 up to 15 years, thus minimizing the problem of reverse causality.