Effect of Intraperitoneal Selenium Administration on Liver Glycogen Levels in Rats Subjected to Acute Forced Swimming

There are a few of studies examining how selenium, which is known to reduce oxidative damage in exercise, influences glucose metabolism and exhaustion in physical activity. The present study aims to examine how selenium administration affects liver glycogen levels in rats subjected to acute swimming...

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Bibliographic Details
Published in:Biological trace element research 2011-03, Vol.139 (3), p.341-346
Main Authors: Akil, Mustafa, Bicer, Mursel, Kilic, Mehmet, Avunduk, Mustafa Cihat, Mogulkoc, Rasim, Baltaci, Abdulkerim Kasim
Format: Article
Language:English
Subjects:
Animals
Biochemistry
Biomedical and Life Sciences
Biotechnology
computer software
ethanol
Exercise
Glucose
glycogen
image analysis
Injections, Intraperitoneal
Life Sciences
light microscopes
Liver
Liver - drug effects
Liver Glycogen - metabolism
Male
metabolism
Nutrition
Oncology
Physical Conditioning, Animal - physiology
Random Allocation
Rats
Rats, Sprague-Dawley
Rodents
Selenium
Sodium
sodium selenite
Sodium Selenite - administration & dosage
Sodium Selenite - pharmacology
swimming
Swimming - physiology
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Summary:There are a few of studies examining how selenium, which is known to reduce oxidative damage in exercise, influences glucose metabolism and exhaustion in physical activity. The present study aims to examine how selenium administration affects liver glycogen levels in rats subjected to acute swimming exercise. The study included 32 Sprague–Dawley type male rats, which were equally allocated to four groups: Group 1, general control; Group 2; selenium-supplemented control (6 mg/kg/day sodium selenite); Group 3, swimming control; Group 4, selenium-supplemented swimming (6 mg/kg/day sodium selenite). Liver tissue samples collected from the animals at the end of the study were fixed in 95% ethyl alcohol. From the tissue samples buried into paraffin, 5-µm cross-sections were obtained using a microtome, put on a microscope slide, and stained with PAS. Stained preparations were assessed using a Nikon Eclipse E400 light microscope. All images obtained with the light microscope were transferred to a PC and evaluated using Clemex PE 3.5 image analysis software. The highest liver glycogen levels were found in groups 1 and 2 (p 
ISSN:0163-4984
1559-0720
DOI:10.1007/s12011-010-8667-4