Comparison of Long-Term Survival of Men Versus Women With Heart Failure Treated With Cardiac Resynchronization Therapy

Cardiac resynchronization therapy (CRT) is an established treatment of patients with heart failure. Several baseline characteristics can influence the CRT outcomes, and little is known about the effect of gender. The aim of the present study was to elucidate the gender-related differences in long-te...

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Bibliographic Details
Published in:The American journal of cardiology 2011-07, Vol.108 (1), p.63-68
Main Authors: Mooyaart, Eline A.Q., MD, Marsan, Nina Ajmone, MD, van Bommel, Rutger J., MD, Thijssen, Joep, MD, Borleffs, C. Jan Willem, MD, PhD, Delgado, Victoria, MD, PhD, van der Wall, Ernst E., MD, PhD, Schalij, Martin J., MD, PhD, Bax, Jeroen J., MD, PhD
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Cardiac Resynchronization Therapy - methods
Cardiology. Vascular system
Cardiovascular
Clinical outcomes
Echocardiography
Electrocardiography
Female
Follow-Up Studies
Gender differences
Heart
Heart failure
Heart Failure - diagnosis
Heart Failure - mortality
Heart Failure - therapy
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Humans
Male
Medical sciences
Netherlands - epidemiology
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Sex Distribution
Sex Factors
Survival analysis
Survival Rate - trends
Time Factors
Treatment Outcome
Ultrasonic imaging
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Summary:Cardiac resynchronization therapy (CRT) is an established treatment of patients with heart failure. Several baseline characteristics can influence the CRT outcomes, and little is known about the effect of gender. The aim of the present study was to elucidate the gender-related differences in long-term survival after CRT. A total of 578 consecutive patients with heart failure underwent CRT. At baseline and 6 months after CRT, the clinical and echocardiographic parameters were obtained. All-cause mortality was compared between the men and women. The study population included 431 men (67 ± 9 years) and 147 women (65 ± 11 years). No differences in the clinical and echocardiographic characteristics were observed between the men and women, except for left bundle branch block and a nonischemic etiology of heart failure, which were more frequent in women (81% vs 68% and 63% vs 33%, respectively; p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2011.02.345