Intestinal physiology and regulatory T cell response to immediate or delayed access to feed and water in Pekin ducklings

• Published in: Poultry science 2011-09, Vol.90 (9), p.2041-2046
• Main Authors: Loudon, A. H, Shanmugasundaram, R, Lilburn, M. S, Selvaraj, R. K
• Format: Article
• Language: English
• Subjects: Animal Feed; Animal Husbandry; Animals; Body Weight; ducklings; Ducks - growth & development; Ducks - physiology; duodenum; Gene Expression Regulation; interleukin-10; Interleukin-2 Receptor alpha Subunit - metabolism; Intestines - growth & development; Intestines - physiology; long term effects; messenger RNA; mucins; Mucins - analysis; pancreas; pathogens; Pekin; physiology; RNA, Messenger - genetics; RNA, Messenger - metabolism; T-Lymphocytes, Regulatory - physiology; Time Factors; Water
• ISSN: 0032-5791; 1525-3171
• DOI: 10.3382/ps.2011-01347

This study investigated the effects of delayed access to feed and water on early duckling growth, selected aspects of intestinal physiology, and immune responses. Ducklings were assigned to one of 2 experimental groups. In one treatment group (referred to as the fed group), feed and water were provided beginning on d 0, and in the other treatment group (referred to as the withheld group), feed and water were withheld until d 2. The ducklings in the withheld treatment had lower BW at 2 and 6 d posthatch than ducklings in the fed group. At 8 d posthatch (6 d postfeeding), the BW of the ducklings in the withheld group was comparable to the BW of the 6-d-old ducklings in the fed group. At 2 d posthatch, withheld ducklings had lower absolute and relative duodenum plus pancreas weight than fed ducklings. At 8 d posthatch (6 d postfeeding), withheld ducklings had higher absolute and relative duodenum plus pancreas weight than fed ducklings at 6 d posthatch. At 2 d posthatch, mucin 5B mRNA content was approximately 2 times lower in withheld ducklings (P = 0.09) than in fed ducklings. At 6 d posthatch, mucin 5b mRNA content was approximately 2.5-fold higher in withheld ducklings (P = 0.07) than in fed ducklings. Delayed access to feed and water increased the CD25+ cell number in the cecal tonsil at 2, 6, and 8 d posthatch. The IL-10 content of CD25+ cells was higher in the withheld ducklings than in the fed ducklings at 2 and 6 d posthatch. In conclusion, delaying access of ducklings with no experimental pathogen infection to feed and water has no long-term effects on early growth parameters, intestinal physiology, and immune responses.