Could cortical signals control intraspinal stimulators? A theoretical evaluation

In this paper, we examine the control signals that are required to generate stepping using two different intraspinal microstimulation (ISMS) paradigms and discuss the theoretical feasibility of controlling ISMS-evoked stepping using a brain computer interface. Tonic (constant amplitude) and phasic (...

Full description

Saved in:
Bibliographic Details
Published in:IEEE transactions on neural systems and rehabilitation engineering 2006-06, Vol.14 (2), p.198-201
Main Authors: Mushahwar, V.K., Guevremont, L., Saigal, R.
Format: Article
Language:English
Subjects:
Animals
Biomedical engineering
Cats
Cerebral Cortex - physiopathology
Control systems
Electric Stimulation Therapy - methods
Extremities
Feasibility Studies
Feedback
Functional electrical stimulation
Gait Disorders, Neurologic - etiology
Gait Disorders, Neurologic - physiopathology
Gait Disorders, Neurologic - rehabilitation
intraspinal microstimulation
Lighting control
locomotion
Male
Protocols
Signal generators
Signal restoration
Spinal Cord - physiopathology
Spinal Cord Injuries - complications
Spinal Cord Injuries - physiopathology
Spinal Cord Injuries - rehabilitation
Spinal cord injury
Switches
Therapy, Computer-Assisted - methods
User-Computer Interface
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this paper, we examine the control signals that are required to generate stepping using two different intraspinal microstimulation (ISMS) paradigms and discuss the theoretical feasibility of controlling ISMS-evoked stepping using a brain computer interface. Tonic (constant amplitude) and phasic (modulated amplitude) ISMS protocols were used to produce stepping in the hind limbs of paralyzed cats. Low-amplitude tonic ISMS activated a spinal locomotor-like network that resulted in bilateral stepping of the hind limbs. Phasic ISMS generated coordinated stepping by simultaneously activating flexor synergies in one limb coupled with extensor synergies in the other. Using these ISMS paradigms, we propose that one or two independent cortical signals will be adequate for controlling ISMS-induced stepping after SCI.
ISSN:1534-4320
1558-0210
DOI:10.1109/TNSRE.2006.875532