Reduction of nitro-substituted compounds by native and immobilizedEscherichia coli cells

Reduction of nitro-substituted compounds, 1,4-benzodiazepine-2-ones, dibenzo[b,f]-1,4-diaz-epines, quinolones, and quinoxalinones, byEscherichia coli cells was studied. Physicochemical methods demonstrated the formation of corresponding amines. 4-(p-Nitrophenyl)-1H-6-R-quinolones-2 were nor reduced...

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Bibliographic Details
Published in:Applied biochemistry and microbiology 2000-01, Vol.36 (1), p.63-68
Main Authors: Davidenko, T I, Bondarenko, G I
Format: Article
Language:English
Subjects:
Amines
Bacteria
Benzodiazepines
Carrageenan
carrageenans
Immobilization
Nitro compounds
Quinolones
Reduction
Substitutes
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Summary:Reduction of nitro-substituted compounds, 1,4-benzodiazepine-2-ones, dibenzo[b,f]-1,4-diaz-epines, quinolones, and quinoxalinones, byEscherichia coli cells was studied. Physicochemical methods demonstrated the formation of corresponding amines. 4-(p-Nitrophenyl)-1H-6-R-quinolones-2 were nor reduced byEscherichia coli cells. Regiospecific reduction of 2,4-dinitro-5H-l l-(p-R-phenyl)-dibenzo[b,f]-1,4-diazepines and 4-(2′-R-3′,5′-dinitro)-benzoyl-3,4-dihydroquinoxalinones-2 was shown to result in the formation of 2-nitro-4-amino-5H-11-(p-R-phenyl)-dibenzo[b,f]-1,4-diazepines and 4-(2′-R-3′-nitro-5′-amino)-benzoyl-3,4-dihydroquinoxalinones-2, respectively. Methods for microbiological reduction of nitro compounds and immobilization ofEscherichia coli cells into carrageenan and its modified forms were elaborated.
ISSN:0003-6838
1608-3024
DOI:10.1007/BF02738137