Feline immunodeficiency virus infection: clinicopathologic findings in 90 naturally occurring cases

In 90 cats with naturally occurring feline immunodeficiency virus (FIV) infection, the clinicopathologic changes seen at the time of first diagnosis of FIV infection included lymphopenia (29%), neutrophilia (27%), monocytosis (23%), anemia (18%), leukocytosis (13%), leukopenia (13%), neutropenia (11...

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Bibliographic Details
Published in:Journal of veterinary internal medicine 1993-03, Vol.7 (2), p.85-90
Main Authors: Sparkes, A.H, Hopper, C.D, Millard, W.G, Gruffydd-Jones, T.J, Harbour, D.A
Format: Article
Language:English
Subjects:
AIDS/HIV
ANIMAL DISEASES
Animals
BLOOD DISORDERS
CATS
CHAT
CYTOPENIAS
DEFICIENCE IMMUNOLOGIQUE
DEFICIENCIA INMUNOLOGICA
ENFERMEDADES DE LOS ANIMALES
Feline immunodeficiency virus
Female
GATO
Hematologic Diseases - microbiology
Hematologic Diseases - veterinary
Immunodeficiency Virus, Feline
IMMUNOLOGICAL DEFICIENCY
LENTIVIRINAE
Lentivirus Infections - blood
Lentivirus Infections - veterinary
MALADIE DES ANIMAUX
Male
PATHOLOGIE
PATHOLOGY
PATOLOGIA
TRASTORNOS SANGUINEOS
TROUBLE SANGUIN
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Summary:In 90 cats with naturally occurring feline immunodeficiency virus (FIV) infection, the clinicopathologic changes seen at the time of first diagnosis of FIV infection included lymphopenia (29%), neutrophilia (27%), monocytosis (23%), anemia (18%), leukocytosis (13%), leukopenia (13%), neutropenia (11%), hyperproteinemia (38%), and hyperglobulinemia (25%). Forty‐nine (54%) of the cats showed multiple hematologic abnormalities, and a further 24 (17%) had a single abnormality. The most consistent changes in serum protein electrophoretic patterns were increases in the concentrations of alpha2 globulin and gammaglobulin subfractions. Although there is no established system for staging the degree of immunosuppression in cats infected with FIV, cytopenias appeared to be more commnn in cats with advanced clinical signs of disease.
ISSN:0891-6640
1939-1676
DOI:10.1111/j.1939-1676.1993.tb03174.x