Body Mass Index is Related with Bronchial Function and Reversibility in Children with Allergic Rhinitis and Asthma

Several studies have outlined a possible relationship between an increased body mass index and respiratory allergic diseases, such as asthma and rhinitis. The aim of the study was to analyse the relationship between BMI and lung function, including bronchodilation test, in allergic children. The stu...

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Bibliographic Details
Published in:International journal of immunopathology and pharmacology 2011-10, Vol.24 (4_suppl), p.21-24
Main Authors: Ciprandi, G, Brambilla, I, Tosca, Ma, Arrigo, T, Salpietro, A, Leonardi, S, La Rosa, M, Marseglia, Gl
Format: Article
Language:English
Subjects:
Adolescent
Asthma - diagnosis
Asthma - epidemiology
Asthma - physiopathology
Body Mass Index
Bronchi - physiopathology
Bronchodilator Agents
Child
Female
Forced Expiratory Flow Rates - physiology
Forced Expiratory Volume - physiology
Humans
Male
Respiratory Function Tests
Rhinitis, Allergic, Perennial - diagnosis
Rhinitis, Allergic, Perennial - epidemiology
Rhinitis, Allergic, Perennial - physiopathology
Rhinitis, Allergic, Seasonal - diagnosis
Rhinitis, Allergic, Seasonal - epidemiology
Rhinitis, Allergic, Seasonal - physiopathology
Skin Tests
Spirometry
Vital Capacity - physiology
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Summary:Several studies have outlined a possible relationship between an increased body mass index and respiratory allergic diseases, such as asthma and rhinitis. The aim of the study was to analyse the relationship between BMI and lung function, including bronchodilation test, in allergic children. The study included 153 children (103 males, mean age 12.8 years) with allergic rhinitis and mild asthma. All subjects were evaluated performing skin prick test, spirometry, and bronchodilalation test. BMI values were in the normal range as well as lung function. BMI significantly related with FEV1, FVC values and FEV1/FVC ratio both before and after bronchodilation. In conclusion, this study provides the first evidence that BMI is negatively related with bronchial reversibility in children with allergic rhinitis and asthma. As reversibility is related with bronchial inflammation, this finding might underline a link between overweight and allergic inflammation.
ISSN:0394-6320
2058-7384
DOI:10.1177/03946320110240S405