Management of chronic kidney disease in the elderly

Both chronic kidney disease (CKD) and end‐stage renal disease are strongly age related. Although the morbidity and mortality of CKD have significantly improved in recent years because of a greater understanding of its pathophysiology and evidence‐based approach to management, the application of this...

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Bibliographic Details
Published in:Internal medicine journal 2011-11, Vol.41 (11), p.761-768
Main Authors: Ng, B. L., Anpalahan, M.
Format: Article
Language:English
Subjects:
Age Factors
Aged
chronic kidney disease
CKD-MBD
dialysis
Disease Management
elderly
ESRD
Humans
hypertension
Kidney Failure, Chronic - diagnosis
Kidney Failure, Chronic - epidemiology
Kidney Failure, Chronic - therapy
Renal Dialysis - methods
Renal Insufficiency, Chronic - diagnosis
Renal Insufficiency, Chronic - epidemiology
Renal Insufficiency, Chronic - therapy
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Summary:Both chronic kidney disease (CKD) and end‐stage renal disease are strongly age related. Although the morbidity and mortality of CKD have significantly improved in recent years because of a greater understanding of its pathophysiology and evidence‐based approach to management, the application of this evidence to the elderly CKD patients is often fraught with difficulty. This is because, besides age, the clinical and biological variables that are widely prevalent in the elderly, such as multiple co‐morbidities, functional impairments and polypharmacy, and quality of life and functional outcome measures, which are pertinent to this age group, have generally not been incorporated into the available evidence. This paper reviews the current evidence with a view to providing a framework for diagnosing and managing CKD in the elderly. Special references are made to age‐related physiological changes in the renal system, assessment of renal function, and management of metabolic complications and end‐stage renal disease.
ISSN:1444-0903
1445-5994
DOI:10.1111/j.1445-5994.2011.02590.x