A naturally occurring nanomaterial from the Sundew (Drosera) for tissue engineering

In recent years advances have been made in the design of novel materials for tissue engineering through the use of polysaccharides. This study evaluated the ability of a naturally secreted polysaccharide adhesive from the Sundew (Drosera capensis) as a support for cell growth. The Sundew adhesive ha...

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Bibliographic Details
Published in:Bioinspiration & biomimetics 2011-12, Vol.6 (4), p.046009-1-8
Main Authors: Lenaghan, S C, Serpersu, K, Xia, L, He, W, Zhang, M
Format: Article
Language:English
Subjects:
Adhesives
Adhesives - chemistry
Animals
Attachment
Biocompatible Materials - chemistry
Biological Products - chemistry
Bones
Cell Adhesion - physiology
Cell Culture Techniques - methods
Cell Proliferation
Cell Survival - physiology
Drosera - chemistry
Humans
Materials Testing
Nanocomposites
Nanomaterials
Nanostructure
Nanostructures - chemistry
PC12 Cells
Polysaccharides
Polysaccharides - chemistry
Rats
Tissue engineering
Tissue Engineering - methods
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Summary:In recent years advances have been made in the design of novel materials for tissue engineering through the use of polysaccharides. This study evaluated the ability of a naturally secreted polysaccharide adhesive from the Sundew (Drosera capensis) as a support for cell growth. The Sundew adhesive has several advantages including its high elasticity and antibiotic nature. By coating glass cover slips with the Sundew adhesive, a network of nanofibers was generated that was capable of promoting attachment and differentiation of a model neuronal cell line, PC-12. We also demonstrated the potential of this material for repairing bone and soft tissue injuries, by testing attachment of osteoblasts and endothelial cells. Finally, it was determined that the Sundew biomaterial was stable through testing by atomic force microscopy and prolonged cell growth. This work has proven the capabilities of using a nanomaterial derived from the Sundew adhesive for the purpose of tissue engineering.
ISSN:1748-3182
1748-3190
DOI:10.1088/1748-3182/6/4/046009