Lower associated costs using rifampicin-miconazole‒impregnated catheters compared with standard catheters

Previous cost-effectiveness analyses found that antibiotic-impregnated catheters decrease the incidence of catheter-related bloodstream infection (CRBSI) as well as the costs related to central venous catheter (CVC) use, including increased hospital length of stay. The effect varied greatly among th...

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Bibliographic Details
Published in:American journal of infection control 2011-12, Vol.39 (10), p.895-897
Main Authors: Lorente, Leonardo, MD, PhD, Lecuona, María, MD, PhD, Ramos, María José, MD, Jiménez, Alejandro, PhD, Mora, María L., MD, PhD, Sierra, Antonio, MD, PhD
Format: Article
Language:English
Subjects:
Adult
Aged
Anti-Bacterial Agents - economics
Anti-Bacterial Agents - therapeutic use
Antibiotics
bacteremia
Bacteremia - economics
Bacteremia - epidemiology
Bacteremia - prevention & control
Blood
Catheter-Related Infections - economics
Catheter-Related Infections - epidemiology
Catheter-Related Infections - prevention & control
Catheters
coated
Cohort Studies
Cost analysis
Cross Infection - economics
Cross Infection - epidemiology
Cross Infection - prevention & control
effectiveness
efficiency
Female
Health Care Costs - statistics & numerical data
Health care expenditures
Humans
Incidence
Infection Control
Infectious Disease
Male
Miconazole - economics
Miconazole - therapeutic use
Middle Aged
Nosocomial infections
Retrospective Studies
Rifampin - economics
Rifampin - therapeutic use
Venous
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Summary:Previous cost-effectiveness analyses found that antibiotic-impregnated catheters decrease the incidence of catheter-related bloodstream infection (CRBSI) as well as the costs related to central venous catheter (CVC) use, including increased hospital length of stay. The effect varied greatly among the studies, however. In this retrospective cohort study, compared with standard catheters, the use of rifampicin-miconazole–impregnated catheters was associated with lower CRBSI incidence and immediate CVC-related costs (taking into account only the costs of CVC, diagnosis, and treatment of CRBSI) ( P < .001). Our data indicate that the use of rifampicin-miconazole–impregnated catheters can save associated costs.
ISSN:0196-6553
1527-3296
DOI:10.1016/j.ajic.2011.01.018