Eczema Increases Susceptibility to PM10 in Office Indoor Environments

The objective was to compare impact of indoor office environment on employees with eczema with those without eczema. Exposure was measured at 56 sites and modelled for 173 work places. Tear film stability, lysozyme in nasal lavage, immunoglobulin E (IgE), and Phadiatop were assessed, and symptoms an...

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Bibliographic Details
Published in:Archives of environmental & occupational health 2012-01, Vol.67 (1), p.15-21
Main Authors: Bakke, Jan Vilhelm, Wieslander, Gunilla, Norback, Dan, Moen, Bente E.
Format: Article
Language:English
Subjects:
Adult
Air Pollutants, Occupational - adverse effects
Air Pollutants, Occupational - analysis
Air Pollution, Indoor - adverse effects
Air Pollution, Indoor - analysis
atopy
Case-Control Studies
Cross-Sectional Studies
Dermatitis, Atopic - immunology
Dermatitis, Atopic - physiopathology
eczema
Facial Dermatoses - etiology
Female
Flushing - etiology
Humans
Immunoglobulin E - blood
indoor environment
Linear Models
lysozyme
Male
Middle Aged
Muramidase - metabolism
Nasal Lavage Fluid - chemistry
Occupational Exposure - adverse effects
Occupational Exposure - analysis
occupational medicine
Particulate Matter - adverse effects
Particulate Matter - analysis
PM10
Surveys and Questionnaires
Tears
Universities
Workplace
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Summary:The objective was to compare impact of indoor office environment on employees with eczema with those without eczema. Exposure was measured at 56 sites and modelled for 173 work places. Tear film stability, lysozyme in nasal lavage, immunoglobulin E (IgE), and Phadiatop were assessed, and symptoms and perceptions collected by questionnaires. Multiple regression analyses were applied, adjusted for age, gender, strain, current smoking, and respiratory infections. Those with eczema perceived temperature too high but not associated with measured temperature. They had increased lysozyme in nasal lavage associated with increased air temperature difference between 6 and 10 am, more general and mucosal symptoms, and "dry or flushed facial skin" associated with airborne particulate matter less than 10 microns in diameter (PM 10 ). Impact of PM 10 was most pronounced among those with eczema previous 30 days. Having eczema might be an important predictor for subjective and objective responses to indoor environment.
ISSN:1933-8244
2154-4700
2154-4700
DOI:10.1080/19338244.2011.564236