Psychomotor recovery and blood propofol level in colonoscopy when using propofol sedation

Background It is commonly recommended that patients refrain from driving for 24 hours after endoscopy for which sedation is given. Objective The aim of this study was to evaluate psychomotor recovery and blood propofol concentrations after colonoscopy with propofol sedation to determine whether driv...

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Bibliographic Details
Published in:Gastrointestinal endoscopy 2012-03, Vol.75 (3), p.506-512
Main Authors: Horiuchi, Akira, MD, Nakayama, Yoshiko, MD, Fujii, Hideyasu, Katsuyama, Yoshihiko, PhD, Ohmori, Shigeru, PhD, Tanaka, Naoki, MD
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Colonoscopy
Conscious Sedation
Digestive system. Abdomen
Endoscopy
Female
Gastroenterology and Hepatology
Gastroenterology. Liver. Pancreas. Abdomen
General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation
Humans
Hypnotics and Sedatives - blood
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Propofol - blood
Prospective Studies
Psychomotor Performance
Recovery of Function
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Summary:Background It is commonly recommended that patients refrain from driving for 24 hours after endoscopy for which sedation is given. Objective The aim of this study was to evaluate psychomotor recovery and blood propofol concentrations after colonoscopy with propofol sedation to determine whether driving might be safe. Design A prospective, consecutive study. Setting Municipal hospital outpatients. Patients This study involved 48 consecutive patients scheduled for colonoscopy with propofol sedation. Intervention Patient clinical features, psychomotor recovery, and blood concentrations of propofol were assessed. Psychomotor recovery was assessed before colonoscopy and 1 and 2 hours after colonoscopy by using the number connection test and a driving simulator test. Main Outcome Measurements Clinical features, psychomotor recovery, and blood concentration of propofol. Results All patients successfully completed the post-sedation assessments. Although there was a significant difference in results of the number connection test between before colonoscopy and 1 hour after colonoscopy, all number connection test results were within normal limits (
ISSN:0016-5107
1097-6779
DOI:10.1016/j.gie.2011.08.020