Cardiac arrest and myocardial pseudoinfarction

Recently, CMR has shown several patterns of myocardial oedema and fi brosis with a high sensitivity and specifi city for cardiac sarcoid osis.1 As in our case, transmural involvement can mimic coronary artery disease, so the clinical context is impor tant. In a prospective study of 81 patients, both...

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Bibliographic Details
Published in:The Lancet (British edition) 2012-03, Vol.379 (9820), p.1074-1074
Main Authors: Gunawardana, Nushan P, Dr, Keenan, Niall G, MD, Moon, James C, MD, Rakhit, Roby, MD
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiac arrest
Cardiomyopathies - complications
Cardiomyopathies - diagnosis
Cardiovascular disease
Corticoids
Female
General aspects
Heart Arrest - etiology
Heart attacks
Humans
Internal Medicine
Medical sciences
Middle Aged
Mortality
Myocardial Infarction - diagnosis
Sarcoidosis
Sarcoidosis - complications
Sarcoidosis - diagnosis
Ventricular Fibrillation - etiology
Citations: Items that this one cites
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Summary:Recently, CMR has shown several patterns of myocardial oedema and fi brosis with a high sensitivity and specifi city for cardiac sarcoid osis.1 As in our case, transmural involvement can mimic coronary artery disease, so the clinical context is impor tant. In a prospective study of 81 patients, both cardiac and event-free survival were shown to be higher in sarcoidosis patients with no cardiac involvement on CMR (97% vs 71% at 3 years).1 Other markers of poorer prognosis include heart failure, impaired left ventricular systolic function, ventricular arrhythmias, and not receiving corticosteroids. 4 Retro spective studies have shown that corticosteroids improve 5-year survival from 10% to 90%.4 Steroids should be started in symptomatic patients (ie arrhythmia or left ventricular impairment), but there is no prospective evidence of benefi t in patients with subclinical cardiac involvement.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(11)61818-7