Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China

In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy in...

Full description

Saved in:
Bibliographic Details
Published in:Molecular biology reports 2010-12, Vol.37 (8), p.3889-3895
Main Authors: Zhu, Bo-feng, Yang, Guang, Shen, Chun-mei, Qin, Hai-xia, Fan, Shuan-liang, Deng, Li-bin, Chen, Feng, Chen, Li-ping, Wang, Hong-dan, Wang, Zhen-yuan, Lucas, Rudolf, Lian, Zhen-min
Format: Article
Language:English
Subjects:
Animal Anatomy
Animal Biochemistry
Biomedical and Life Sciences
China
Chromosomes, Human - genetics
Data processing
Enumeration
Ethnic Groups - genetics
Forensic science
Gene frequency
Gene Frequency - genetics
Gene loci
Gene polymorphism
Genetic Loci - genetics
Genetic relationship
Genetics, Population
Geography
Histology
Humans
Life Sciences
Microsatellite Repeats - genetics
Morphology
Phylogeny
Population genetics
Russia
Russian population
STR
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.
ISSN:0301-4851
1573-4978
DOI:10.1007/s11033-010-0045-y