Cascade stomach is associated with upper gastrointestinal symptoms: a population-based study

Background  Cascade stomach (CS) is recognized by characteristic findings on barium studies. We prospectively investigated the relationship between CS and upper gastrointestinal (GI) symptoms. Methods  In subjects undergoing health screening, CS was diagnosed by barium studies. Consecutive persons (...

Full description

Saved in:
Bibliographic Details
Published in:Neurogastroenterology and motility 2012-05, Vol.24 (5), p.451-455
Main Authors: Kusano, M., Hosaka, H., Moki, H., Shimoyama, Y., Kawamura, O., Kuribayashi, S., Mori, M., Akuzawa, M.
Format: Article
Language:English
Subjects:
Abdominal Pain - complications
Abdominal Pain - epidemiology
Adult
Barium
Body Mass Index
Contrast Media
dyspepsia
Dyspepsia - complications
Dyspepsia - epidemiology
dyspepsia symptoms
epigastralgia symptoms
Female
gastric morphology
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - epidemiology
Gastrointestinal Diseases - complications
Gastrointestinal Diseases - epidemiology
gastroptosis
Humans
Japan - epidemiology
Male
Middle Aged
Population
Population studies
Prospective Studies
reflux symptoms
Regression analysis
Risk Factors
Stomach
Stomach - anatomy & histology
Stomach - pathology
Stomach Diseases - complications
Stomach Diseases - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background  Cascade stomach (CS) is recognized by characteristic findings on barium studies. We prospectively investigated the relationship between CS and upper gastrointestinal (GI) symptoms. Methods  In subjects undergoing health screening, CS was diagnosed by barium studies. Consecutive persons (500 men and 127 women) with CS were identified and the same number of age‐matched subjects without CS were selected as controls. Upper GI symptoms were classified as reflux symptoms, dyspepsia symptoms, or epigastralgia symptoms. Then, we prospectively analyzed barium studies to classify the gastric morphology and also assessed upper GI symptoms in consecutive 5008 men and 2736 women. Key Results  BMI was significantly higher in men with CS than in controls, and also in women with CS than in controls. Upper GI symptoms were significantly more frequent in the CS group than the controls among both men and women, especially reflux symptoms. In men, logistic regression analysis identified CS as an independent risk factor for upper GI symptoms (odds ratio = 1.771, P = 0.005) and for reflux symptoms (odds ratio = 2.07, P = 0.009). In women, CS was also significantly related to upper GI symptoms (odds ratio = 2.544, P = 0.020). The prevalence of CS was significantly higher (P 
ISSN:1350-1925
1365-2982
DOI:10.1111/j.1365-2982.2012.01876.x