Inability To Make a Premortem Diagnosis of Acanthamoeba Species Infection in a Patient with Fatal Granulomatous Amebic Encephalitis

Granulomatous amebic encephalitis (GAE), an infection of immunocompromised hosts, is almost uniformly fatal. A case of GAE in a patient who failed to mount a serologic response to Acanthamoeba polyphaga is presented. Although Acanthamoeba polyphaga that is sensitive to multiple antimicrobials grew f...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2005-06, Vol.43 (6), p.3003-3006
Main Authors: Bloch, Karen C, Schuster, Frederick L
Format: Article
Language:English
Subjects:
Acanthamoeba - isolation & purification
Aged
Amebiasis - diagnosis
Amebiasis - parasitology
Animals
Biological and medical sciences
Case Reports
Encephalitis - diagnosis
Encephalitis - parasitology
Fatal Outcome
Female
Fundamental and applied biological sciences. Psychology
Granuloma - diagnosis
Granuloma - parasitology
Humans
Infectious diseases
Medical sciences
Microbiology
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Description
Summary:Granulomatous amebic encephalitis (GAE), an infection of immunocompromised hosts, is almost uniformly fatal. A case of GAE in a patient who failed to mount a serologic response to Acanthamoeba polyphaga is presented. Although Acanthamoeba polyphaga that is sensitive to multiple antimicrobials grew from brain tissue, an inability to make a premortem diagnosis precluded therapy.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.43.6.3003-3006.2005